6bij

X-ray diffraction
2.1Å resolution

HLA-DRB1 in complex with citrullinated fibrinogen peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-135307 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class II histocompatibility antigen, DR alpha chain Chain: A
Molecule details ›
Chain: A
Length: 177 amino acids
Theoretical weight: 20.6 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01903 (Residues: 29-205; Coverage: 77%)
Gene names: HLA-DRA, HLA-DRA1
Sequence domains:
Structure domains:
HLA class II histocompatibility antigen, DRB1 beta chain Chain: B
Molecule details ›
Chain: B
Length: 189 amino acids
Theoretical weight: 22.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01911 (Residues: 31-219; Coverage: 80%)
Gene name: HLA-DRB1
Sequence domains:
Structure domains:
Fibrinogen beta chain Chain: C
Molecule details ›
Chain: C
Length: 13 amino acids
Theoretical weight: 1.29 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P02675 (Residues: 69-81; Coverage: 3%)
Gene name: FGB

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: C2221
Unit cell:
a: 67.01Å b: 177.71Å c: 77.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.181 0.239
Expression systems:
  • Homo sapiens
  • Not provided