› 5y50

X-ray diffraction
2.6Å resolution

Crystal structure of eukaryotic MATE transporter AtDTX14

Released:
DOI: 10.2210/pdb5y50/pdb
PDB entry 5y50 coloured by chain, front view.
PDB entry 5y50 coloured by chain, side view.
PDB entry 5y50 coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Structural basis for xenobiotic extrusion by eukaryotic MATE transporter.
Miyauchi H, Moriyama S, Kusakizako T, Kumazaki K, Nakane T, Yamashita K, Hirata K, Dohmae N, Nishizawa T, Ito K, Miyaji T, Moriyama Y, Ishitani R, Nureki O
Nat Commun 8 1633 (2017)
PMID: 29158478

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189934 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein DETOXIFICATION 14 Chain: A
Molecule details ›
Chain: A
Length: 461 amino acids
Theoretical weight: 49.54 KDa
Source organism: Arabidopsis thaliana
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9C994 (Residues: 20-473; Coverage: 94%)
Gene names: At1g71140, DTX14, F23N20.13
Sequence domains: MatE

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32XU
Spacegroup: P212121
Unit cell:
a: 52.8Å b: 86.78Å c: 116.43Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.224 0.276
Expression system: Spodoptera frugiperda

Quick links

Citations

9 review citations

Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria.
Alav et al. (2021)
8 more

9 mentions without citation

Cellular export of sugars and amino acids: role in feeding other cells and organisms.
Kim et al. (2021)
8 more