› 5xi7

X-ray diffraction
2.99Å resolution

Crystal structure of T2R-TTL bound with PO-7

Released:
DOI: 10.2210/pdb5xi7/pdb
PDB entry 5xi7 coloured by chain, front view.
PDB entry 5xi7 coloured by chain, side view.
PDB entry 5xi7 coloured by chain, top view.
Source organisms:
Entry authors: Chu Y, Wang Y, Yang J, Li W

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-236641 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Tubulin alpha chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 450 amino acids
Theoretical weight: 50.04 KDa
Source organism: Sus barbatus
UniProt:
  • Canonical: A0A0R4I993 (Residues: 1-450; Coverage: 100%)
Sequence domains:
Structure domains:
Tubulin beta chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 445 amino acids
Theoretical weight: 50 KDa
Source organism: Sus barbatus
UniProt:
  • Canonical: A0A0R4I995 (Residues: 1-445; Coverage: 100%)
Sequence domains:
Structure domains:
Stathmin-4 Chain: E
Molecule details ›
Chain: E
Length: 184 amino acids
Theoretical weight: 21.64 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P63043 (Residues: 6-189; Coverage: 97%)
Gene name: Stmn4
Sequence domains: Stathmin family
Structure domains: Methane Monooxygenase Hydroxylase; Chain G, domain 1
Tubulin tyrosine ligase Chain: F
Molecule details ›
Chain: F
Length: 384 amino acids
Theoretical weight: 44.38 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
Structure domains:

Ligands and Environments

7 bound ligands:
Ligand GTP 3 x GTP
Ligand MG 4 x MG
Ligand CA 3 x CA
Ligand GDP 1 x GDP
Ligand MES 2 x MES
Ligand PO7 2 x PO7
Ligand ACP 1 x ACP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 105.251Å b: 157.375Å c: 182.467Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.222 0.266
Expression system: Escherichia coli

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