› 5u6g

X-ray diffraction
2.6Å resolution

Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal

Released:
DOI: 10.2210/pdb5u6g/pdb
PDB entry 5u6g coloured by chain, front view.
PDB entry 5u6g coloured by chain, side view.
PDB entry 5u6g coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Assar Z, Geiger JH

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156129 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Retinol-binding protein 2 Chains: A, B, C, D, E, F, H, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, H, J, K, L
Length: 133 amino acids
Theoretical weight: 15.58 KDa
Source organism: Homo sapiens
Expression system: Bacteria
UniProt:
  • Canonical: P50120 (Residues: 2-134; Coverage: 99%)
Gene names: CRBP2, RBP2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin
Retinol-binding protein 2 Chains: G, I
Molecule details ›
Chains: G, I
Length: 133 amino acids
Theoretical weight: 15.6 KDa
Source organism: Homo sapiens
Expression system: Bacteria
UniProt:
  • Canonical: P50120 (Residues: 2-134; Coverage: 99%)
Gene names: CRBP2, RBP2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand RET 11 x RET
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P212121
Unit cell:
a: 65.474Å b: 73.597Å c: 351.601Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.177 0.28
Expression system: Bacteria

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