Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Regulator of chromosome condensation, RCC1
- Armadillo
- Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
- Importin-alpha, importin-beta-binding domain
- Atypical Arm repeat
- Armadillo-like helical
- Importin-alpha, importin-beta-binding domain superfamily
- Armadillo-type fold
1 more domain
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126371 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit alpha-3
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 521 amino acids
Theoretical weight: 57.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 521 amino acids
Theoretical weight: 57.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
O00629 (Residues: 1-521; Coverage: 100%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Regulator of chromosome condensation
Molecule details ›
Chains: I, J, K, L, M, N, O, P
Length: 421 amino acids
Theoretical weight: 45.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Regulator of chromosome condensation (RCC1) repeat
Structure domains: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Length: 421 amino acids
Theoretical weight: 45.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P18754 (Residues: 1-421; Coverage: 100%)
Sequence domains: Regulator of chromosome condensation (RCC1) repeat
Structure domains: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 21-ID-F
Spacegroup:
P1
Expression system: Escherichia coli BL21(DE3)
