› 5suw

X-ray diffraction
2.3Å resolution

Crystal Structure of ToxT from Vibrio Cholerae O395 bound to 3-(8-Methyl-1,2,3,4-tetrahydronaphthalen-1-yl)propanoic acid

Released:
DOI: 10.2210/pdb5suw/pdb
PDB entry 5suw coloured by chain, front view.
PDB entry 5suw coloured by chain, side view.
PDB entry 5suw coloured by chain, top view.
Source organism: Vibrio cholerae O395
Entry authors: Kull FJ, Kelley AR

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107564 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TCP pilus virulence regulatory protein Chain: A
Molecule details ›
Chain: A
Length: 276 amino acids
Theoretical weight: 32.09 KDa
Source organism: Vibrio cholerae O395
Expression system: Escherichia coli
UniProt:
  • Canonical: A5F384 (Residues: 1-276; Coverage: 100%)
Gene names: VC0395_A0363, VC395_0854, tcpN, toxT
Sequence domains: Helix-turn-helix domain
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand 70G 1 x 70G
Ligand MES 2 x MES
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P212121
Unit cell:
a: 40.31Å b: 81.11Å c: 83.85Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.172 0.168 0.23
Expression system: Escherichia coli

Quick links