› 5khb

Solution NMR

Structure of Phenol-soluble modulin Alpha1

Released:
DOI: 10.2210/pdb5khb/pdb
PDB entry 5khb coloured by chain, ensemble of 20 models, front view.
PDB entry 5khb coloured by chain, ensemble of 20 models, side view.
PDB entry 5khb coloured by chain, ensemble of 20 models, top view.
Source organism: Staphylococcus aureus
Primary publication:
Solution Structures of Phenol-Soluble Modulins α1, α3, and β2, Virulence Factors from Staphylococcus aureus.
Towle KM, Lohans CT, Miskolzie M, Acedo JZ, van Belkum MJ, Vederas JC
Biochemistry 55 4798-806 (2016)
PMID: 27525453

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143160 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phenol-soluble modulin alpha 1 peptide Chain: A
Molecule details ›
Chain: A
Length: 21 amino acids
Theoretical weight: 2.29 KDa
Source organism: Staphylococcus aureus
Expression system: Not provided
UniProt:
  • Canonical: P0C7Y1 (Residues: 1-21; Coverage: 100%)
Gene names: SAOUHSC_00411.4, psmA1
Sequence domains: Phenol-soluble modulin alpha peptide family

Ligands and Environments

No bound ligands
1 modified residue:
Ligand FME 1 x FME

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 51%
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

4 review citations

Staphylococcus aureus Secreted Toxins and Extracellular Enzymes.
Tam et al. (2019)
3 more

2 mentions without citation

Staphylococcus aureus Phenol-Soluble Modulins α1-α3 Act as Novel Toll-Like Receptor (TLR) 4 Antagonists to Inhibit HMGB1/TLR4/NF-κB Signaling Pathway.
Chu et al. (2018)
1 more