› 5jme

X-ray diffraction
2.34Å resolution

Crystal structure of acetylcholine binding protein (AChBP) from Aplysia Californica in complex with alpha-conotoxin PeIA

Released:
DOI: 10.2210/pdb5jme/pdb
PDB entry 5jme coloured by chain, front view.
PDB entry 5jme coloured by chain, side view.
PDB entry 5jme coloured by chain, top view.
Source organisms:
Entry authors: Bobango J, Sankaran B, McIntosh JM, Talley TT

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172937 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 230 amino acids
Theoretical weight: 26.21 KDa
Source organism: Aplysia californica
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8WSF8 (Residues: 18-236; Coverage: 100%)
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain
Structure domains: Neurotransmitter-gated ion-channel ligand-binding domain
Alpha-conotoxin PeIA Chains: F, G, H, I
Molecule details ›
Chains: F, G, H, I
Length: 17 amino acids
Theoretical weight: 1.66 KDa
Source organism: Conus pergrandis
Expression system: Not provided
UniProt:
  • Canonical: Q1L777 (Residues: 22-37; Coverage: 42%)
Sequence domains: Alpha conotoxin precursor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: C2221
Unit cell:
a: 145.115Å b: 147.89Å c: 146.309Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.196 0.228
Expression systems:
  • Homo sapiens
  • Not provided

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