› 5ip5

X-ray diffraction
1.66Å resolution

Human DJ-1 complexed with Na-K-tartrate

Released:
DOI: 10.2210/pdb5ip5/pdb
PDB entry 5ip5 coloured by chain, front view.
PDB entry 5ip5 coloured by chain, side view.
PDB entry 5ip5 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lee S, Cha S-S, An YJ

Function and Biology Details

Reaction catalysed: 
An N(6)-(1-hydroxy-2-oxopropyl)-[protein]-L-lysine + H(2)O = a [protein]-L-lysine + lactate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189205 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Parkinson disease protein 7 Chain: A
Molecule details ›
Chain: A
Length: 189 amino acids
Theoretical weight: 20.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99497 (Residues: 1-189; Coverage: 100%)
Gene name: PARK7
Sequence domains: DJ-1/PfpI family
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
Ligand TLA 1 x TLA
1 modified residue:
Ligand MSE 5 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P3121
Unit cell:
a: 74.802Å b: 74.802Å c: 75.819Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.143 0.142 0.164
Expression system: Escherichia coli

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