Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
- Thiol-activated cytolysin
- Ly-6 antigen/uPA receptor-like
- Snake toxin-like superfamily
- CD59 antigen, conserved site
- Thiol-activated cytolysin C-terminal
- Thiol-activated cytolysin, C-terminal domain superfamily
- Thiol-activated cytolysin, alpha-beta domain superfamily
- Thiol-activated cytolysin superfamily
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109767 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Thiol-activated cytolysin C-terminal domain-containing protein
Molecule details ›
Chains: A, B
Length: 490 amino acids
Theoretical weight: 54.21 KDa
Source organism: Gardnerella vaginalis
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 490 amino acids
Theoretical weight: 54.21 KDa
Source organism: Gardnerella vaginalis
Expression system: Escherichia coli
UniProt:
- Canonical:
B2YGA4 (Residues: 29-516; Coverage: 100%)
Sequence domains:
CD59 glycoprotein
Molecule details ›
Chains: C, D
Length: 78 amino acids
Theoretical weight: 9.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: u-PAR/Ly-6 domain
Structure domains: CD59
Length: 78 amino acids
Theoretical weight: 9.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P13987 (Residues: 26-102; Coverage: 75%)
Sequence domains: u-PAR/Ly-6 domain
Structure domains: CD59
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup:
P21212
Expression system: Escherichia coli
