› 5i6r

X-ray diffraction
2.15Å resolution

Crystal Structure of srGAP2 F-BARx WT Form-1

Released:
DOI: 10.2210/pdb5i6r/pdb
PDB entry 5i6r coloured by chain, front view.
PDB entry 5i6r coloured by chain, side view.
PDB entry 5i6r coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Sporny M, Guez-Haddad J, Isupov MN, Opatowsky Y

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130824 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SLIT-ROBO Rho GTPase-activating protein 2 Chain: A
Molecule details ›
Chain: A
Length: 484 amino acids
Theoretical weight: 56.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O75044 (Residues: 1-484; Coverage: 45%)
Gene names: ARHGAP34, FNBP2, KIAA0456, SRGAP2, SRGAP2A
Sequence domains: Fes/CIP4, and EFC/F-BAR homology domain

Ligands and Environments

3 bound ligands:
Ligand MLT 1 x MLT
Ligand ACT 2 x ACT
Ligand PGE 1 x PGE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P2
Unit cell:
a: 93.3Å b: 29.76Å c: 94.63Å
α: 90° β: 92.99° γ: 90°
R-values:
R R work R free
0.206 0.203 0.26
Expression system: Escherichia coli BL21

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