› 5fmh

X-ray diffraction
1.8Å resolution

Crystal structure of the E405K mutant of human apoptosis inducing factor

Released:
DOI: 10.2210/pdb5fmh/pdb
PDB entry 5fmh coloured by chain, front view.
PDB entry 5fmh coloured by chain, side view.
PDB entry 5fmh coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Sevrioukova I

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132061 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apoptosis-inducing factor 1, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 510 amino acids
Theoretical weight: 55.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O95831 (Residues: 104-613; Coverage: 83%)
Gene names: AIF, AIFM1, PDCD8
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand FAD 1 x FAD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2
Unit cell:
a: 109.3Å b: 49.23Å c: 81.48Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.191 0.243
Expression system: Escherichia coli BL21(DE3)

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