5eat Summary



The structure was published by Starks, C.M., Back, K., Chappell, J., and Noel, J.P., in 1997 in a paper entitled "Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 1997.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of 5-EPI-ARISTOLOCHENE SYNTHASE. This molecule has the UniProt identifier Q40577 (5EAS_TOBAC)search. The sample contained 548 residues which is 100% of the natural sequence. Out of 548 residues 532 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A 5-EPI-ARISTOLOCHENE SYNTHASE Q40577 (1-548) (5EAS_TOBAC)search Nicotiana tabacumsearch 98% 548 97%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q40577 (1 - 548) 5-EPI-ARISTOLOCHENE SYNTHASE Nicotiana tabacum

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q40577) Terpenoid cyclase N-terminal domainsearch, Terpenoid cyclase C-terminal domainsearch Isoprenoid Synthase - domain 1search, Farnesyl Diphosphate Synthasesearch PF01397: Terpene synthase, N-terminal domainsearch, PF03936: Terpene synthase family, metal binding domainsearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A (Q40577) cytoplasmsearch lyase activitysearch magnesium ion bindingsearch terpene synthase activitysearch metal ion bindingsearch terpenoid biosynthetic processsearch metabolic processsearch

Chain InterPro annotation
A Terpene synthase, N-terminal domainsearch Terpene synthase, metal-binding domainsearch Terpenoid cyclases/protein prenyltransferase alpha-alpha toroidsearch Terpenoid synthasesearch