› 5d8t

X-ray diffraction
1.2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196912 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA oligonucleotide containing (S)-C5'-Me-2'-FU Chains: A, B
Molecule details ›
Chains: A, B
Length: 8 nucleotides
Theoretical weight: 2.62 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand NCO 4 x NCO
1 modified residue:
Ligand CBV 2 x CBV

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P43212
Unit cell:
a: 31.172Å b: 31.172Å c: 84.325Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.121 0.12 0.157
Expression system: Not provided

Quick links

Citations

3 review citations

The chemical evolution of oligonucleotide therapies of clinical utility.
Khvorova et al. (2017)
2 more