Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156521 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit alpha-1
Molecule details ›
Chain: A
Length: 447 amino acids
Theoretical weight: 48.45 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 447 amino acids
Theoretical weight: 48.45 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
P52293 (Residues: 72-497; Coverage: 81%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Squamous cell carcinoma antigen recognized by T-cells 3
Molecule details ›
Chain: B
Length: 55 amino acids
Theoretical weight: 6.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Length: 55 amino acids
Theoretical weight: 6.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q15020 (Residues: 601-649; Coverage: 5%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
PAL/PLS BEAMLINE 5C (4A)
Spacegroup:
P212121
Expression system: Escherichia coli
