5z0w

X-ray diffraction
1.9Å resolution

Crystal structure of HIV-1 fusion inhibitor SC29EK complexed with gp41 NHR (N36)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-137985 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transmembrane protein gp41 Chain: E
Molecule details ›
Chain: E
Length: 36 amino acids
Theoretical weight: 4.13 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: P04578 (Residues: 546-581; Coverage: 4%)
Gene name: env
peptide-C Chain: F
Molecule details ›
Chain: F
Length: 29 amino acids
Theoretical weight: 3.75 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: R3
Unit cell:
a: 56.925Å b: 56.925Å c: 51.454Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.208 0.206 0.257
Expression system: Not provided