› 5vbb

X-ray diffraction
1.94Å resolution

Human RNA Pseudouridylate Synthase Domain Containing 1

Released:
DOI: 10.2210/pdb5vbb/pdb
PDB entry 5vbb coloured by chain, front view.
PDB entry 5vbb coloured by chain, side view.
PDB entry 5vbb coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: DONG A, ZENG H, WALKER JR, Bountra C, Arrowsmith CH, Edwards AM, BROWN PJ, WU H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193814 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA pseudouridylate synthase domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 261 amino acids
Theoretical weight: 29.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UJJ7 (Residues: 1-261; Coverage: 84%)
Gene names: C16orf40, RLUCL, RPUSD1
Sequence domains: RNA pseudouridylate synthase

Ligands and Environments

3 bound ligands:
Ligand SO4 3 x SO4
Ligand CL 2 x CL
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 55.2Å b: 92.44Å c: 88.89Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.179 0.224
Expression system: Escherichia coli BL21(DE3)

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