5tez

X-ray diffraction
1.7Å resolution

TCR F50 recgonizing M1-HLA-A2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-230779 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Matrix protein 1 Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 966 Da
Source organism: Influenza A virus
Expression system: Not provided
UniProt:
  • Canonical: P03485 (Residues: 58-66; Coverage: 4%)
Gene name: M
HLA class I histocompatibility antigen, A alpha chain Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04439 (Residues: 25-299; Coverage: 81%)
Gene names: HLA-A, HLAA
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 20-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
TCR F50 alpha chain Chain: I
Molecule details ›
Chain: I
Length: 208 amino acids
Theoretical weight: 23.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins
TCR F50 beta chain Chain: J
Molecule details ›
Chain: J
Length: 243 amino acids
Theoretical weight: 27.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P21
Unit cell:
a: 66.266Å b: 71.053Å c: 100.693Å
α: 90° β: 96.22° γ: 90°
R-values:
R R work R free
0.191 0.19 0.224
Expression systems:
  • Not provided
  • Escherichia coli