› 5szo

X-ray diffraction
3.61Å resolution

Protocadherin Gamma B7 extracellular cadherin domains 1-4 P41212 crystal form

Released:
DOI: 10.2210/pdb5szo/pdb
PDB entry 5szo coloured by chain, front view.
PDB entry 5szo coloured by chain, side view.
PDB entry 5szo coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
γ-Protocadherin structural diversity and functional implications.
Goodman KM, Rubinstein R, Thu CA, Mannepalli S, Bahna F, Ahlsén G, Rittenhouse C, Maniatis T, Honig B, Shapiro L
Elife 5 (2016)
PMID: 27782885

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187596 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Cadherin domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 423 amino acids
Theoretical weight: 47.3 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q91XX3 (Residues: 31-445; Coverage: 46%)
Gene name: Pcdhgb7
Sequence domains:
Structure domains: Cadherins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
2 bound ligands:
Ligand MAN 8 x MAN
Ligand CA 18 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P41212
Unit cell:
a: 97.15Å b: 97.15Å c: 312.39Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.242 0.279
Expression system: Homo sapiens

Quick links

Citations

12 review citations

Regulation of neural circuit formation by protocadherins.
Peek et al. (2017)
11 more

4 mentions without citation

Visualization of clustered protocadherin neuronal self-recognition complexes.
Brasch et al. (2019)
3 more