› 5l5c

X-ray diffraction
6Å resolution

Plexin A1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup P4(3)2(1)2

Released:
DOI: 10.2210/pdb5l5c/pdb
PDB entry 5l5c coloured by chain, front view.
PDB entry 5l5c coloured by chain, side view.
PDB entry 5l5c coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural Basis for Plexin Activation and Regulation.
Kong Y, Janssen BJ, Malinauskas T, Vangoor VR, Coles CH, Kaufmann R, Ni T, Gilbert RJ, Padilla-Parra S, Pasterkamp RJ, Jones EY
Neuron 91 548-60 (2016)
PMID: 27397516

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159713 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (6 distinct):
Plexin-A1 Chain: A
Molecule details ›
Chain: A
Length: 1212 amino acids
Theoretical weight: 134.02 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P70206 (Residues: 37-1236; Coverage: 64%)
Gene names: Kiaa4053, Plxna1
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P43212
Unit cell:
a: 198.15Å b: 198.15Å c: 228.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.305 0.305 0.316
Expression system: Homo sapiens

Quick links

Citations

14 review citations

Macrophage Clearance of Apoptotic Cells: A Critical Assessment.
Gordon et al. (2018)
13 more

4 mentions without citation

Architecture of the Sema3A/PlexinA4/Neuropilin tripartite complex.
Lu et al. (2021)
3 more