› 5kg8

Electron Microscopy
9.1Å resolution

Rigor myosin X co-complexed with an actin filament

Released:
DOI: 10.2210/pdb5kg8/pdb
PDB entry 5kg8 coloured by chain, front view.
PDB entry 5kg8 coloured by chain, side view.
PDB entry 5kg8 coloured by chain, top view.
Source organisms:
Primary publication:
The myosin X motor is optimized for movement on actin bundles.
Ropars V, Yang Z, Isabet T, Blanc F, Zhou K, Lin T, Liu X, Hissier P, Samazan F, Amigues B, Yang ED, Park H, Pylypenko O, Cecchini M, Sindelar CV, Sweeney HL, Houdusse A
Nat Commun 7 12456 (2016)
PMID: 27580874
Related structures: EMD-8244

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159325 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Unconventional myosin-X Chain: A
Molecule details ›
Chain: A
Length: 739 amino acids
Theoretical weight: 85.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HD67 (Residues: 3-741; Coverage: 36%)
Gene names: KIAA0799, MYO10
Sequence domains:
Actin, alpha skeletal muscle Chains: B, C, D
Molecule details ›
Chains: B, C, D
Length: 375 amino acids
Theoretical weight: 41.83 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 3-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 9.1Å
Relevant EMDB volumes: EMD-8244
Expression system: Escherichia coli

Quick links

Citations

9 review citations

MyTH4-FERM myosins in the assembly and maintenance of actin-based protrusions.
Weck et al. (2017)
8 more

3 mentions without citation

The myosin X motor is optimized for movement on actin bundles.
Ropars et al. (2016)
2 more