› 5hmj

X-ray diffraction
1.3Å resolution

Re-refinement of 4xan: hen lysozyme with carboplatin in sodium bromide solution

Released:
DOI: 10.2210/pdb5hmj/pdb
PDB entry 5hmj coloured by chain, front view.
PDB entry 5hmj coloured by chain, side view.
PDB entry 5hmj coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Re-refinement of 4xan: hen egg-white lysozyme with carboplatin in sodium bromide solution.
Tanley SW, Schreurs AM, Kroon-Batenburg LM, Helliwell JR
Acta Crystallogr F Struct Biol Commun 72 251-2 (2016)
PMID: 26919531

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132831 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysozyme C Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.33 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P00698 (Residues: 19-147; Coverage: 100%)
Gene name: LYZ
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

5 bound ligands:
Ligand BR 14 x BR
Ligand NA 1 x NA
Ligand PT 1 x PT
Ligand ACT 1 x ACT
Ligand DMS 2 x DMS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P43212
Unit cell:
a: 78.58Å b: 78.58Å c: 37.29Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.167 0.164 0.215

Quick links

Citations

8 citation in other articles

Characterizing metal-binding sites in proteins with X-ray crystallography.
Handing et al. (2018)
7 more

1 mention without citation

Re-refinement of 4xan: hen egg-white lysozyme with carboplatin in sodium bromide solution.
Tanley et al. (2016)