› 5h9c

X-ray diffraction
1.78Å resolution

Crystal structure of the ASLV fusion protein core

Released:
DOI: 10.2210/pdb5h9c/pdb
PDB entry 5h9c coloured by chain, front view.
PDB entry 5h9c coloured by chain, side view.
PDB entry 5h9c coloured by chain, top view.
Source organism: Rous sarcoma virus (strain Schmidt-Ruppin A)
Primary publication:
Structural characterization of a fusion glycoprotein from a retrovirus that undergoes a hybrid 2-step entry mechanism.
Aydin H, Smrke BM, Lee JE
FASEB J 27 5059-71 (2013)
PMID: 24036886

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-237265 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope glycoprotein gp95 Chain: A
Molecule details ›
Chain: A
Length: 94 amino acids
Theoretical weight: 10.58 KDa
Source organism: Rous sarcoma virus (strain Schmidt-Ruppin A)
Expression system: Escherichia coli
Structure domains: Helix Hairpins

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: R3
Unit cell:
a: 42.8Å b: 42.8Å c: 119.428Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.16 0.158 0.199
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Fusion of Enveloped Viruses in Endosomes.
White et al. (2016)
1 more

1 mention without citation

Structure of the Core Postfusion Porcine Endogenous Retrovirus Fusion Protein.
Dean et al. (2022)