› 5dd4

X-ray diffraction
2.56Å resolution

Apo structure of transcriptional factor AraR from Bacteroides thetaiotaomicron VPI

Released:
DOI: 10.2210/pdb5dd4/pdb
PDB entry 5dd4 coloured by chain, front view.
PDB entry 5dd4 coloured by chain, side view.
PDB entry 5dd4 coloured by chain, top view.
Source organism: Bacteroides thetaiotaomicron VPI-5482
Primary publication:
A novel transcriptional regulator of L-arabinose utilization in human gut bacteria.
Chang C, Tesar C, Li X, Kim Y, Rodionov DA, Joachimiak A
Nucleic Acids Res 43 10546-59 (2015)
PMID: 26438537

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183797 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nudix hydrolase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 228 amino acids
Theoretical weight: 26.62 KDa
Source organism: Bacteroides thetaiotaomicron VPI-5482
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8AAV8 (Residues: 1-225; Coverage: 100%)
Gene name: BT_0354
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand EDO 1 x EDO
Ligand ACT 1 x ACT
1 modified residue:
Ligand MSE 9 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I213
Unit cell:
a: 123.735Å b: 123.735Å c: 123.735Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.183 0.222
Expression system: Escherichia coli

Quick links

Citations

3 review citations

If you eat it, or secrete it, they will grow: the expanding list of nutrients utilized by human gut bacteria.
Glowacki et al. (2020)
2 more

1 mention without citation

A novel transcriptional regulator of L-arabinose utilization in human gut bacteria.
Chang et al. (2015)