Function and Biology Details
Reactions catalysed:
ATP + [biotin carboxyl-carrier protein]-biotin-N(6)-L-lysine + hydrogencarbonate- = ADP + phosphate + [biotin carboxyl-carrier protein]-carboxybiotin-N(6)-L-lysine
ATP + acetyl-CoA + HCO(3)(-) = ADP + phosphate + malonyl-CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
- ClpP/crotonase-like domain superfamily
- Biotin/lipoyl attachment
- Biotin carboxylase, C-terminal
- Acetyl-coenzyme A carboxyltransferase, C-terminal
- Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- Acetyl-coenzyme A carboxyltransferase, N-terminal
- Acetyl-CoA carboxylase, central domain
8 more domains
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Acetyl-CoA carboxylase (preferred)
PDBe Complex ID:
PDB-CPX-169488 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetyl-CoA carboxylase
Molecule details ›
Q00955Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X25
Spacegroup:
P43212
Expression system: Escherichia coli
