5bn9

X-ray diffraction
1.69Å resolution

Crystal structure of ADP bound human Hsp70 NBD mutant R272K.

Released:
Source organism: Homo sapiens
Entry authors: Narayanan D, Engh RA

Function and Biology Details

Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-143649 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heat shock 70 kDa protein 1A Chain: A
Molecule details ›
Chain: A
Length: 388 amino acids
Theoretical weight: 42.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0DMV8 (Residues: 1-388; Coverage: 61%)
Gene names: HSP72, HSPA1, HSPA1A, HSX70
Sequence domains: Hsp70 protein
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 45.933Å b: 63.21Å c: 143.872Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.201
Expression system: Escherichia coli BL21(DE3)