Function and Biology Details
Reaction catalysed:
Release of an N-terminal amino acid, Cys-|-Xaa-, in which the half-cystine residue is involved in a disulfide loop, notably in oxytocin or vasopressin. Hydrolysis rates on a range of aminoacyl arylamides exceed that for the cystinyl derivative, however.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165395 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Leucyl-cystinyl aminopeptidase, pregnancy serum form
Molecule details ›
Chains: A, B
Length: 912 amino acids
Theoretical weight: 104.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Structure domains:
Length: 912 amino acids
Theoretical weight: 104.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9UIQ6 (Residues: 111-111, 155-1025; Coverage: 85%)
Sequence domains:
Structure domains:
Ligands and Environments
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I03
Spacegroup:
P21
Expression systems:
- Homo sapiens
- Not provided
