4xrw

X-ray diffraction
1.79Å resolution

Crystal structure of the di-domain ARO/CYC BexL from the BE-7585A biosynthetic pathway

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112870 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative cyclase Chain: A
Molecule details ›
Chain: A
Length: 329 amino acids
Theoretical weight: 36.24 KDa
Source organism: Amycolatopsis orientalis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D7RFJ9 (Residues: 1-309; Coverage: 100%)
Gene name: bexL
Sequence domains: Polyketide cyclase / dehydrase and lipid transport
Structure domains: Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P41212
Unit cell:
a: 63.68Å b: 63.68Å c: 170.371Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.18 0.219
Expression system: Escherichia coli BL21(DE3)