4v46 Summary

pdbe.org/4v46
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PDB entry 4v46 (supersedes 1otz,1p0t)

Crystal structure of the BAFF-BAFF-R complex

The structure was published by Kim, H.M., Yu, K.S., Lee, M.E., et al., Yoo, O.J., Lee, H., and Lee, J.-O., in 2003 in a paper entitled "Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.3 Å and deposited in 2003.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Tumor necrosis factor ligand superfamily member 13B and Tumor necrosis factor receptor superfamily member 13C.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The most likely quaternary structure is a 120meric assembly.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
AA Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AB Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AC Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AD Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AE Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AF Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AG Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AH Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AI Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AJ Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AK Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AL Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AM Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AN Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AO Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AP Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AQ Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AR Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AS Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AT Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AU Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AV Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AW Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AX Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AY Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
AZ Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
A0 Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
A1 Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
A2 Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
A3 Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
A4 Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
A5 Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
A6 Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
A7 Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
A8 Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
A9 Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Aa Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ab Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ac Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ad Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ae Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Af Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ag Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ah Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ai Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Aj Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ak Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Al Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Am Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
An Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ao Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ap Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Aq Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ar Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
As Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
At Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Au Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Av Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Aw Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
Ax Tumor necrosis factor ligand superfamily member 13B Q9Y275 (138-285) (TN13B_HUMAN)search Homo sapienssearch < 90% 148 97%
BA Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BB Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BC Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BD Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BE Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BF Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BG Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BH Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BI Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BJ Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BK Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BL Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BM Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BN Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BO Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BP Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BQ Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BR Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BS Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BT Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BU Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BV Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BW Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BX Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BY Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
BZ Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
B0 Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
B1 Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
B2 Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
B3 Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
B4 Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
B5 Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
B6 Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
B7 Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
B8 Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
B9 Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Ba Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bb Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bc Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bd Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Be Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bf Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bg Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bh Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bi Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bj Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bk Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bl Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bm Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bn Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bo Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bp Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bq Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Br Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bs Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bt Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bu Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bv Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bw Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%
Bx Tumor necrosis factor receptor superfamily member 13C Q96RJ3 (1-63) (TR13C_HUMAN)search Homo sapienssearch < 90% 63 39%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
Q9Y275 (138 - 285) Tumor necrosis factor ligand superfamily member 13B Homo sapiens
Q96RJ3 (1 - 63) Tumor necrosis factor receptor superfamily member 13C Homo sapiens

Chain Sequence family (Pfam)
AA, AB, AC, AD, AE, AF, AG, AH, AI, AJ, AK, AL, AM, AN, AO, AP, AQ, AR, AS, AT, AU, AV, AW, AX, AY, AZ, A0, A1, A2, A3, A4, A5, A6, A7, A8, A9, Aa, Ab, Ac, Ad, Ae, Af, Ag, Ah, Ai, Aj, Ak, Al, Am, An, Ao, Ap, Aq, Ar, As, At, Au, Av, Aw, Ax TNF(Tumour Necrosis Factor) familysearch
BA, BB, BC, BD, BE, BF, BG, BH, BI, BJ, BK, BL, BM, BN, BO, BP, BQ, BR, BS, BT, BU, BV, BW, BX, BY, BZ, B0, B1, B2, B3, B4, B5, B6, B7, B8, B9, Ba, Bb, Bc, Bd, Be, Bf, Bg, Bh, Bi, Bj, Bk, Bl, Bm, Bn, Bo, Bp, Bq, Br, Bs, Bt, Bu, Bv, Bw, Bx BAFF-R, TALL-1 bindingsearch