HIGH RESOLUTION CRYSTAL STRUCTURE OF A HUMAN TNF-ALPHA MUTANT
The structure was published by Cha, S.S., Kim, J.S., Cho, H.S., et al., Kim, Y.J., Hahn, J.H., and Oh, B.H., in 1998 in a paper entitled "High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 1997.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of TUMOR NECROSIS FACTOR-ALPHA. This molecule has the UniProt identifier P01375 (TNFA_HUMAN). The sample contained 150 residues which is < 90% of the natural sequence. Out of 150 residues 143 were observed and are deposited in the PDB.
The molecule most likely forms homotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: