4tnc Summary

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PDB entry 4tnc (supersedes 3tnc)

REFINED STRUCTURE OF CHICKEN SKELETAL MUSCLE TROPONIN C IN THE TWO-CALCIUM STATE AT 2-ANGSTROMS RESOLUTION

The structure was published by Satyshur, K.A., Rao, S.T., Pyzalska, D., Drendel, W., Greaser, M., and Sundaralingam, M., in 1988 in a paper entitled "Refined structure of chicken skeletal muscle troponin C in the two-calcium state at 2-A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1987.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of TROPONIN C. This molecule has the UniProt identifier P02588 (TNNC2_CHICK)search. The sample contained 162 residues which is 99% of the natural sequence. Out of 162 residues 159 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A TROPONIN C P02588 (3-163) (TNNC2_CHICK)search Gallus gallussearch 98% 162 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P02588 (3 - 163) TROPONIN C Gallus gallus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P02588) Calmodulin-likesearch EF-handsearch PF00036: EF handsearch, PF13499: EF-hand domain pairsearch, PF13833: EF-hand domain pairsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (P02588) skeletal muscle contractionsearch metal ion bindingsearch calcium ion bindingsearch actin bindingsearch troponin complexsearch

Chain InterPro annotation
A EF-hand domainsearch EF-hand domain pairsearch EF-Hand 1, calcium-binding sitesearch