› 4pz0

X-ray diffraction
1.25Å resolution

The crystal structure of a solute binding protein from Bacillus anthracis str. Ames in complex with quorum-sensing signal autoinducer-2 (AI-2)

Released:
DOI: 10.2210/pdb4pz0/pdb
PDB entry 4pz0 coloured by chain, front view.
PDB entry 4pz0 coloured by chain, side view.
PDB entry 4pz0 coloured by chain, top view.
Source organism: Bacillus anthracis str. Ames
Entry authors: Tan K, Gu M, Kwon K, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105638 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Autoinducer 2-binding protein LsrB Chain: A
Molecule details ›
Chain: A
Length: 324 amino acids
Theoretical weight: 36.02 KDa
Source organism: Bacillus anthracis str. Ames
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A6H3AKG3 (Residues: 27-347; Coverage: 100%)
Gene name: GBAA_2975
Sequence domains: Periplasmic binding protein domain
Structure domains: Rossmann fold

Ligands and Environments

3 bound ligands:
Ligand PAV 1 x PAV
Ligand EDO 7 x EDO
Ligand CL 1 x CL
1 modified residue:
Ligand MSE 7 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 39.005Å b: 58.067Å c: 63.194Å
α: 90° β: 95.58° γ: 90°
R-values:
R R work R free
0.129 0.128 0.149
Expression system: Escherichia coli BL21(DE3)

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