Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1517
The structure was published by Zhang, Z., Ojo, K.K., Vidadala, R., et al., Verlinde, C.L.M.J., Van Voorhis, W.C., and Fan, E., in 2014 in a paper entitled "Potent and Selective Inhibitors of CDPK1 from T. gondii and C. parvum Based on a 5-Aminopyrazole-4-carboxamide Scaffold" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.4 Å and deposited in 2014.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Calmodulin-domain protein kinase 1. This molecule has the UniProt identifier Q9BJF5 (Q9BJF5_TOXGO). The sample contained 484 residues which is 94% of the natural sequence. Out of 484 residues 460 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: