› 4olk

X-ray diffraction
2.69Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112802 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidase C51 domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 168 amino acids
Theoretical weight: 18.9 KDa
Source organism: Staphylococcus phage G15
Expression system: Escherichia coli
UniProt:
  • Canonical: D6QY02 (Residues: 1-165; Coverage: 33%)
Gene names: GH15_071, lysGH15
Sequence domains: CHAP domain
Structure domains: endopeptidase domain like (from Nostoc punctiforme)

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand B3P 1 x B3P
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P6222
Unit cell:
a: 113.359Å b: 113.359Å c: 178.538Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.174 0.204
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Recombinant Endolysins as Potential Therapeutics against Antibiotic-Resistant Staphylococcus aureus: Current Status of Research and Novel Delivery Strategies.
Haddad Kashani et al. (2018)
4 more

7 mentions without citation

Cell Wall Hydrolases in Bacteria: Insight on the Diversity of Cell Wall Amidases, Glycosidases and Peptidases Toward Peptidoglycan.
Vermassen et al. (2019)
6 more