Human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate)
The structure was published by Buchini, S., Gallat, F.X., Greig, I.R., et al., Wakatsuki, S., Chavas, L.M., and Withers, S.G., in 2014 in a paper entitled "Tuning mechanism-based inactivators of neuraminidases: mechanistic and structural insights." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.513 Å and deposited in 2013.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Sialidase-2. This molecule has the UniProt identifier Q9Y3R4 (NEUR2_HUMAN). The sample contained 382 residues which is 100% of the natural sequence. Out of 382 residues 353 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: