Influenza Neuraminidase in complex with a novel antiviral compound
The structure was published by Mohan, S., Kerry, P.S., Bance, N., Niikura, M., and Pinto, B.M., in 2014 in a paper entitled "Serendipitous discovery of a potent influenza virus a neuraminidase inhibitor." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.65 Å and deposited in 2013.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Neuraminidase. This molecule has the UniProt identifier Q07599 (NRAM_I63A3). The sample contained 390 residues which is < 90% of the natural sequence. Out of 390 residues 389 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homotetramers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: