Crystal Structure of Murine Cyclooxygenase-2 Complex with Meloxicam
The structure was published by Xu, S., Hermanson, D.J., Banerjee, S., et al., Clayton, G.M., Garavito, R.M., and Marnett, L.J., in 2014 in a paper entitled "Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.45 Å and deposited in 2013.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Prostaglandin G/H synthase 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: