4kwi

X-ray diffraction
2Å resolution

The crystal structure of angucycline C-6 ketoreductase LanV with bound NADP and 11-deoxy-6-oxylandomycinone

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195640 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Reductase homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 263 amino acids
Theoretical weight: 27.5 KDa
Source organism: Streptomyces cyanogenus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9ZGC1 (Residues: 2-253; Coverage: 100%)
Gene name: lanV
Sequence domains: Enoyl-(Acyl carrier protein) reductase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P41212
Unit cell:
a: 92.61Å b: 92.61Å c: 106.33Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.225
Expression system: Escherichia coli