4kq2 Summary

pdbe.org/4kq2
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Glucose1,2cyclic phosphate bound activated state of Yeast Glycogen Synthase

The structure was published by Chikwana, V.M., Khanna, M., Baskaran, S., et al., Depaoli-Roach, A., Roach, P.J., and Hurley, T.D., in 2013 in a paper entitled "Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.95 Å and deposited in 2013.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Gsy2p.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Gsy2p P27472 (1-705) (GYS2_YEAST)search Saccharomyces cerevisiae S288csearch 100% 724 88%
B Gsy2p P27472 (1-705) (GYS2_YEAST)search Saccharomyces cerevisiae S288csearch 100% 724 88%
C Gsy2p P27472 (1-705) (GYS2_YEAST)search Saccharomyces cerevisiae S288csearch 100% 724 88%
D Gsy2p P27472 (1-705) (GYS2_YEAST)search Saccharomyces cerevisiae S288csearch 100% 724 88%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P27472 (1 - 705) Gsy2p Saccharomyces cerevisiae FostersO

Chain Sequence family (Pfam)
A, B, C, D (P27472) PF05693: Glycogen synthasesearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B, C, D (P27472) glycogen (starch) synthase activitysearch catalytic activitysearch transferase activity, transferring glycosyl groupssearch transferase activitysearch glycogen biosynthetic processsearch metabolic processsearch cytoplasmsearch

Chain InterPro annotation
A, B, C, D Glycogen synthasesearch