4kcf Summary


X-ray Structure of a KijD3 in Complex with FMN and dTDP-3-amino-2,3,6-trideoxy-4-keto-3-methyl-D-glucose

The structure was published by Thoden, J.B., Branch, M.C., Zimmer, A.L., Bruender, N.A., and Holden, H.M., in 2013 in a paper entitled "Active site architecture of a sugar N-oxygenase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.098 Å and deposited in 2013.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of FAD-dependent oxidoreductase. This molecule has the UniProt identifier B3TMR1 (B3TMR1_9ACTO)search. The sample contained 454 residues which is 100% of the natural sequence. Out of 454 residues 407 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A FAD-dependent oxidoreductase B3TMR1 (1-437) (B3TMR1_9ACTO)search Actinomadura kijaniatasearch 100% 454 89%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
B3TMR1 (1 - 437) FAD-dependent oxidoreductase Actinomadura kijaniata

Chain Sequence family (Pfam)
A (B3TMR1) PF00441: Acyl-CoA dehydrogenase, C-terminal domainsearch, PF02770: Acyl-CoA dehydrogenase, middle domainsearch, PF02771: Acyl-CoA dehydrogenase, N-terminal domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A (B3TMR1) flavin adenine dinucleotide bindingsearch oxidoreductase activity, acting on the CH-CH group of donorssearch oxidoreductase activitysearch nucleotide bindingsearch acyl-CoA dehydrogenase activitysearch oxidation-reduction processsearch metabolic processsearch

Chain InterPro annotation
A Acyl-CoA oxidase/dehydrogenase, central domainsearch Acyl-CoA dehydrogenase/oxidase C-terminalsearch Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domainsearch Acyl-CoA dehydrogenase/oxidase, N-terminalsearch