› 4k7t

X-ray diffraction
1.1Å resolution

Structure of the ternary complex of bacitracin, zinc, and geranyl-pyrophosphate

Released:
DOI: 10.2210/pdb4k7t/pdb
PDB entry 4k7t coloured by chain, front view.
PDB entry 4k7t coloured by chain, side view.
PDB entry 4k7t coloured by chain, top view.
Source organism: Bacillus subtilis
Primary publication:
High-resolution crystal structure reveals molecular details of target recognition by bacitracin.
Economou NJ, Cocklin S, Loll PJ
Proc Natl Acad Sci U S A 110 14207-12 (2013)
PMID: 23940351

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164673 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
bacitracin A2 Chain: A
Molecule details ›
Chain: A
Length: 12 amino acids
Theoretical weight: 1.46 KDa
Source organism: Bacillus subtilis

Ligands and Environments

3 bound ligands:
Ligand GPP 1 x GPP
Ligand ZN 1 x ZN
Ligand NA 1 x NA
3 modified residues:
Ligand DGL 1 x DGL
Ligand DPN 1 x DPN
Ligand DAS 1 x DAS

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P62
Unit cell:
a: 35.98Å b: 35.98Å c: 16.12Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.128 0.127 0.149

Quick links

Citations

14 review citations

Novel formulations for antimicrobial peptides.
Carmona-Ribeiro et al. (2014)
13 more

3 mentions without citation

High-resolution crystal structure reveals molecular details of target recognition by bacitracin.
Economou et al. (2013)
2 more