4jw2 Summary

pdbe.org/4jw2
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Selection of specific protein binders for pre-defined targets from an optimized library of artificial helicoidal repeat proteins (alphaRep)

The structure was published by Guellouz, A., Valerio-Lepiniec, M., Urvoas, A., et al., Desmadril, M., van Tilbeurgh, H., and Minard, P., in 2013 in a paper entitled "Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2013.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely A3 artificial protein and bA3-2: binder of A3 protein.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A A3 artificial protein Not available
synthetic constructsearch Not available 108 67%
B bA3-2: binder of A3 protein Not available
synthetic constructsearch Not available 201 94%

Chain InterPro annotation
A PBS lyase HEAT-like repeatsearch Armadillo-like helicalsearch Armadillo-type foldsearch
B HEATsearch PBS lyase HEAT-like repeatsearch Armadillo-like helicalsearch Armadillo-type foldsearch