spacer Crystal Structure of human SIRT3 with ELT inhibitor 3 [14-(4-{2-[(methylsulfonyl)amino]ethyl}piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide]
Experimental details
Structure factors Download
Spacegroup P 65
Parameters
a:120.464Å b:120.464Å c:44.468Å
α:90.0° β:90.0° γ:120.0°
Refinement
Highest Resolution 2.24 Å
Lowest Resolution 39.43 Å
Number of reflections Observed:16756 (97.71% complete) R-free:900 (5.1%)
R-values R = 0.2 Rwork = 0.2 Rfree = 0.25
Diffraction
Dataset 1
Temperature (K) Source Source type Wavelength (Å)
Synchrotron SSRF BEAMLINE BL17U

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