spacer Crystal Structure of human SIRT3 with ELT inhibitor 11c [N-{2-[1-(6-carbamoylthieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl]ethyl}-N'-ethylthiophene-2,5-dicarboxamide]
Experimental details
Structure factors Download
Spacegroup P 65
Parameters
a:119.32Å b:119.32Å c:44.53Å
α:90.0° β:90.0° γ:120.0°
Refinement
Highest Resolution 1.7 Å
Lowest Resolution 40.0 Å
Number of reflections Observed:38011 (99.93% complete) R-free:2006 (5.0%)
R-values R = 0.2 Rwork = 0.2 Rfree = 0.23
Diffraction
Dataset 1
Temperature (K) Source Source type Wavelength (Å)
100.0 Synchrotron SSRF BEAMLINE BL17U

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