Crystal Structure of uPA in complex with its inhibitor 4-bromobenzylamine at pH 7.4
The structure was published by Zhang, X., Jiang, L., Zhao, B., Yuan, C., and Huang, M., in in a paper entitled "Halogen bonds in the design of serine protease inhibitors" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2013.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Urokinase-type plasminogen activator. This molecule has the UniProt identifier P00749 (UROK_HUMAN). The sample contained 247 residues which is < 90% of the natural sequence. Out of 247 residues 246 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: