4jin Summary details

pdbe.org/4jin/summary_details
spacer X-ray crystal structure of Archaeoglobus fulgidus Rio1 bound to (2E)-N-benzyl-2-cyano-3-(pyridine-4-yl)acrylamide (WP1086)
Summary
Header TRANSFERASE/TRANSFERASE INHIBITORsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.095 Å, R-factor: 18.17%, Free R-factor: 24.08%, Spacegroup: P 1 21 1
Released 24/04/2013, deposition: 06/03/2013, last revision: 10/07/2013
Authors Mielecki, M.search; Krawiec, K.search; Kiburu, I.search; Grzelak, K.search; Wlodzimierz, Z.search; Kierdaszuk, B.search; Kowa, K.search; Fokt, I.search; Szymanski, S.search; Piotr, S.search; Szeja, W.search; Priebe, W.search; Lesyng, B.search; LaRonde-LeBlanc, N.search
Primary citation Development of novel molecular probes of the Rio1 atypical protein kinase.
BIOCHIM.BIOPHYS.ACTAsearch vol:1834, pag:1292-1301 (2013) [PubMed 23523885 ]search
Keywords protein kinasesearch, Ribosome Biogenesissearch, pre-40Ssearch, autophosphorylationsearch, TRANSFERASE-TRANSFERASE INHIBITOR complexsearch
EC 2.7.11.1 ExPASy BRENDA search (A)
Organism Archaeoglobus fulgidus DSM 4304 224325search(A)
UniProt O28471search (A)
Solvent A
Related entries 1ztf, 1zp9
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A RIO-type serine/threonine-protein kinase Rio1 Protein O28471 (RIO1_ARCFU)search
258 98%
Heterogens
Chain Id Name Ligands
A (2E)-N-BENZYL-2-CYANO-3-(PYRIDIN-4-YL)PROP-2-ENAMIDE 1L7 search
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