4j9t Summary


Crystal structure of a putative, de novo designed unnatural amino acid dependent metalloprotein, northeast structural genomics consortium target OR61

The structure was published by Mills, J.H., Khare, S.D., Bolduc, J.M., et al., Tong, L., Stoddard, B.L., and Baker, D., in 2013 in a paper entitled "Computational design of an unnatural amino Acid dependent metalloprotein with atomic level accuracy." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.4 Å and deposited in 2013.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of designed unnatural amino acid dependent metalloprotein. This molecule has the UniProt identifier Q02834 (NANH_MICVI)search. The sample contained 363 residues which is < 90% of the natural sequence. Out of 363 residues 355 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A designed unnatural amino acid dependent metalloprotein Q02834 (47-407) (NANH_MICVI)search Micromonospora viridifacienssearch 99% 363 97%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q02834 (47 - 407) designed unnatural amino acid dependent metalloprotein Micromonospora viridifaciens

Chain ID Molecular function (GO)
A (Q02834) exo-alpha-sialidase activitysearch

Chain InterPro annotation
A Sialidasessearch Sialidase familysearch