Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Mitogen-activated protein (MAP) kinase, ERK1/2
- Death effector domain
- Death-like domain superfamily
- Serine/threonine-protein kinase, active site
- Mitogen-activated protein (MAP) kinase, conserved site
- Protein kinase, ATP binding site
- Protein kinase domain
- Protein kinase-like domain superfamily
1 more domain
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-151239 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mitogen-activated protein kinase 1
Molecule details ›
Chains: A, C
Length: 356 amino acids
Theoretical weight: 41.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 356 amino acids
Theoretical weight: 41.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P28482 (Residues: 8-360; Coverage: 98%)
Sequence domains: Protein kinase domain
Structure domains:
Astrocytic phosphoprotein PEA-15
Molecule details ›
Chain: B
Length: 97 amino acids
Theoretical weight: 11.24 KDa
Source organism: Cricetulus griseus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Death effector domain
Structure domains: Death Domain, Fas
Length: 97 amino acids
Theoretical weight: 11.24 KDa
Source organism: Cricetulus griseus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q9Z297 (Residues: 1-96; Coverage: 74%)
Sequence domains: Death effector domain
Structure domains: Death Domain, Fas
