spacer JAK1 kinase (JH1 domain) in complex with the inhibitor (TRANS-4-{2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(6H)-YL}CYCLOHEXYL)ACETONITRILE
EDS summary (view at EDS site)
Original refinement program REFMAC 5.6.0117
Resolution from map calculation 2.35 - 42.61 Å
R value for map 0.204
Completeness of data 98.1 %
Number of reflections 25708 (25708 in original CIF file)
Yeates <|L|> 0.505
Yeates <L^2> 0.336
Wilson plot B-factor 40.7 Å2
Bulk-solvent scale factor (k) 0.337 e/Å3
Bulk-solvent B-factor 19.3 Å2
Mean (st. dev.) values for non-water residues:
Real-space R-value 0.151 (0.054)
Real-space correlation coefficient 0.936 (0.047)
Occupancy-weighted average temperature factor 35.2 (15.8) Å2

View more detailed information at EDS.

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