spacer JAK2 kinase (JH1 domain) in complex with the inhibitor TRANS-4-[(8AS)-2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(8AH)-YL]CYCLOHEXANECARBONITRILE
UniProt sequence   UniProt   CATH   Pfam   SCOP   Secondary structure   UniProt features   FASTA string  

Chain A: Tyrosine-protein kinase JAK2

1 S G A F E D R D P T Q F E E R H L K F L Q Q L G K G N F G S V E M C R Y D P L Q D N T G E V V A V K K L Q H S T E E H L
61 R D F E R E I E I L K S L Q H D N I V K Y K G V C Y S A G R R N L K L I M E Y L P Y G S L R D Y L Q K H K E R I D H I K
121 L L Q Y T S Q I C K G M E Y L G T K R Y I H R D L A T R N I L V E N E N R V K I G D F G L T K V L P Q D K E X X K V K E
181 P G E S P I F W Y A P E S L T E S K F S V A S D V W S F G V V L Y E L F T Y I E K S K S P P A E F M R M I G N D K Q G Q
241 M I V F H L I E L L K N N G R L P R P D G C P D E I Y M I M T E C W N N N V N Q R P S F R D L A L R V D Q I R D N M A G

Regions

spacer